Dr. Girlfriend / Henchman 21 (voice)
Hank Venture / The Monarch (voice)
Brock Samson (voice)
Dr. Venture (voice)
Dean Venture (voice)
Dr. Orpheus (voice) / Dr. Byron Orpheus / Vincenzo (voice)
Dr. Jonas Venture (voice) / Jonas Venture Sr. (voice)
Triana Orpheus (voice) / Princess Tinglepants (voice)
The Alchemist (voice) / The Alchemist / Mister Sample (voice)
Molotov Cocktease (voice) / Sally Impossible (voice)
Jefferson Twilight (voice) / Mandalay (voice)
Action Johnny (voice) / Sgt. Hatred (voice)
Rocco (voice) / Ramburglar / Illuminati 2 / Illuminati 3 (voice)
Sirena (voice) / Sirena / Nurse (voice)
Wide Wale / Manolo (voice) / Wide Wale / Jägermeister / Janitor (voice)
Tijuana Prostitute (voice) / Kim / Jollyrancher82 (voice)
Redusa (voice) / Thalia / Nikki Fictel / Mrs. Fictel (voice)
Myra Brandish (voice) / Jackie / Greek Lady 1 / Greek Lady 2 / Greek Widows (voice)
S-464 (voice) / Dr. Phineas Phage / Blackout 2 (voice)
Baron Ünderbheit (voice) / Baron Ünderbheit / Otto Aquarius (voice)
Professor Impossible / Alien Villain (voice) / Headshot (voice)
General Treister (voice) / Copycat (voice)
Snoopy (voice) / Dale Hale (voice)
Fallen Archer / Zoo Worker (voice) / Diamond Backdraft / Man in Robe (voice)
