Dante (voice) / Dante / Soldier #1 (voice)
Lady (voice) / Mary (voice)
Vergil (voice) / Vergil / Horned Demon (voice)
Arkham / Agni / Rudra (voice) / Worker (voice)
White Rabbit (voice) / White Rabbit / Soldier #2 (voice)
Eva (voice) / Eva / Baby (voice)
Enzo (voice) / Enzo / Trucker (voice)
Arius (voice)
Baines (voice) / Baines / Soldier #3 (voice)
Baines (voice) / Baines / Demon Commander (voice)
Anders (voice) / Anders / Soldier Thief #1 (voice)
Plasma / Griff (voice) / Demon Hunter #1 / Plasma (voice)
Cavaliere / Demon Man (voice) / Civilian / Predator Demon (voice)
Chi / Baby (voice) / Chi / Secretary (voice)
Tom / Soldier / Demon Prisoner 2 (voice) / Tom / Demon 2 (voice)
Argosax (voice) / DARKCOM Soldier / Chained Demon 2 (voice)
Young Vergil (voice) / Young Vergil / Boy (voice)
Mattie (voice) / Additional Voices (voice)
Kalina (voice) / Mother / Baby / Demon Kid (voice)
Young Dante (voice)
Hobbes / News Anchor 1 / Narrator (voice) / Narrator (voice)
Pres. Hopper / Late Night Host (voice) / Pres. Hopper / Soldier (voice)
Predator Demon (voice) / Goliath / Beelzebubs / General (voice)
King (voice)
