Captain Underpants / Mr. Krupp (voice)
Harold (voice)
George (voice)
Narrator (voice)
Comic Narrator (voice)
Melvin (voice) / Melvin / Melvinborg (voice)
Jessica / Dressy (voice)
Steve 'Gooch' Yamaguchi (voice)
Erica (voice) / Werica Ang (voice)
Ms. Ribble (voice) / Ms. Ribble / Malison Saurus (voice)
Mr. Meaner (voice) / Mr. Meaner / Sergeant Boxers (voice)
Miss Anthrope (voice) / Miss Anthrope / Clogneta (voice)
Mr. Ree (voice) / Mr. Ree / Splotch (voice)
Rap Talkwell / Mr. Gigglenose (voice) / Robius (voice)
Diddlysaurus / The Schmoozer (voice) / Diddlysaurus / Fingers (voice)
Melvin's Mom (voice) / Harold's Mom / Melvin's Mom (voice)
Cash Networth / Salamangler (voice) / Cash Networth / Lee Dingman (voice)
Ms. Hurd (voice) / Ms. Hurd / DJ Drowsy Drawers (voice)
Lunch Lady (voice) / Ms. Yewh / TP Mummy (voice)
Smartsy Fartsy (voice)
Keithicus / Rippedicus / Guardicus (voice) / Furculees / Chief Hairococha (voice)
Hank (voice) / Laserlightmare (voice)
Lane Junkston (voice)
Tubbadump (voice)
