Miles Morales / Spider-Man (Spin) (voice)
Peter Parker / Spider-Man (Spidey) (voice)
Gwen Stacy / Ghost-Spider (voice)
Norman Osborn / Green Goblin (voice) / Green Goblin (voice)
Carolyn Trainer / Doctor Octopus (voice) / Carolyn Trainer / Dr. Octopus (voice)
Aunt May (voice)
Aleksei Sytsevich / Rhino (voice) / Rhino (voice)
Francine Frye / Electro (voice)
Bruce Banner / Hulk (voice)
Trace-E (voice) / CAL (voice)
Kamala Khan / Ms. Marvel (voice) / Vendor #1 / Civilian #2 / Mother (voice)
T'Challa / Black Panther (voice)
Felicia Hardy / Black Cat (voice) / Black Cat (voice)
Mr. Von Carnegie (voice) / Mr. Von Cornegie / Visitor 3 (voice)
Rio Morales (voice)
Helen Stacy (voice)
Tony Stark / Iron Man (voice)
Jefferson Morales (voice)
William Baker / Sandman (voice)
White Tiger (voice)
