Nick Birch / Maury the Hormone Monster / Coach Steve / Lola Skumpy / Rick the Hormone Monster (voice)
Andrew Glouberman (voice)
Jessi Glaser (voice)
Jay Bilzerian (voice)
Diane Birch / Connie the Hormone Monstress (voice)
Elliot Birch (voice)
Ghost of Duke Ellington (voice)
Matthew (voice)
Missy Foreman-Greenwald (voice)
Caleb (voice) / Caleb / Lump Humpman (voice)
Missy Foreman-Greenwald (voice) / Missy Foreman-Greenwald / Mosaic Missy (voice)
Devin (voice)
Marty Glouberman (voice)
Shannon Glaser (voice) / Shannon Glaser / Grace / Intellect Sphinx (voice)
Lars (voice) / Lars / Detective Dumont / Pornscape Residents (voice)
Barbara Glouberman (voice) / Barbara Glouberman / Bubbe (voice)
Judd Birch (voice) / Garrison Keillor / Magician #1 (voice)
DeVon (voice) / DeVon / Gina's Brother #2 (voice)
Monica Foreman-Greenwald (voice) / Cellsea (voice)
Greg Glaser (voice) / (voice)
Brad (voice) / Wiggles (voice)
(voice) / Vendor (voice)
Nathan Fillion (voice)
Leah Birch (voice) / Leah Birch / Lorraine the Hormone Monstress (voice)
