Dante (voice) / Dante / Soldier #1 (voice)
Lady (voice) / Mary (voice)
Vergil (voice) / Vergil / Horned Demon (voice)
Arkham / Agni / Rudra (voice) / Mundus / Jester / News Anchor 2 (voice)
White Rabbit (voice) / White Rabbit / News Anchor (voice)
Eva (voice) / Eva / Echidna (voice)
Enzo (voice) / Enzo / Trucker (voice)
Arius (voice)
Baines (voice) / Baines / Soldier #3 (voice)
Baines (voice) / Baines / News Anchor 1 (voice)
Anders (voice) / Anders / Soldier Thief #1 (voice)
Plasma / Griff (voice) / Demon Hunter #1 / Plasma (voice)
Cavaliere / Demon (voice) / Cavaliere (voice)
Chi (voice) / Chi / Secretary 1 (voice)
Tom / Soldier (voice) / Tom / Soldier / Demon Prisoner 2 (voice)
Argosax (voice) / DARKCOM Soldier / Chained Demon 2 (voice)
Young Vergil (voice) / Young Vergil / Boy (voice)
Mattie (voice) / Additional Voices (voice)
Mother / News Anchor / Waitress (voice) / Mother / Baby / Demon Kid (voice)
Young Dante (voice)
News Anchor / Senator / Priest (voice) / Hobbes / News Anchor 1 / Narrator (voice)
Hopper / Protester (voice) / Pres. Hopper / Soldier (voice)
Goliath / Beelzebubs / General (voice) / Mushi / Rama (voice)
King (voice)
