Jimmy Neutron (voice)
Sheen Estevez (voice)
Carl Wheezer (voice)
Cindy Vortex (voice) / Cindy Vortex / Tina Sue (voice)
Goddard / Special Vocal Effects (voice) / Goddard / Phantom #4 / Special Vocal Effects (voice)
Hugh Neutron (voice) / Hugh Neutron / General / Alien Man / Emergency System / Gleason Like Creature (voice)
Libby Folfax (voice) / Libby Folfax / Chuck (voice)
Judy Neutron (voice) / Judy Neutron / Woman (voice)
Ms. Fowl (voice) / Ms. Fowl / Lady (voice)
Nick Dean (voice) / Nick Dean / Amber (voice)
Sam Melnick (voice) / Sam Melnick / Lance (voice)
Bolbi (voice) / Bolbi / TV Announcer (voice)
Ultra Lord (voice) / Popbot / Gortox / Goddard Speaking (voice)
Nanobot #2 (voice) / Copbot / Interviewer (voice)
Travoltron/Barbarino (voice) / Positive Jimmy / Negative Jimmy / Macho Jimmy (voice)
Dr. Dark / Pizza Monster (voice) / Rayburn (voice)
Zix / Ticket Taker (voice) / Zix / Tee / Reporter (voice)
Betty Quinlan (voice)
Professor Calamitous (voice)
Mombot (voice) / Elke (voice)
Mr. Estevez (voice)
Nanobot #1 (voice) / Nanobot #1 / Baby Quackers (voice)
Coach Gruber (voice)
Tee (voice) / Tremendous Jackson (voice)
